Xanthine Oxidase Inhibitor

by Abu Zahid Zuhin
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Xanthine Oxidase Inhibitor

If your doctor has prescribed Xanthine Oxidase Inhibitor, you may want to know what purpose it serves. As we are more health-conscious these days, it’s natural to seek how a particular medicine works on us and what side-effects it may cause.

This Xanthine Oxidase drug is used for treating multiple health conditions such as gout, kidney stones, or various malignancies.

In this article, you will get to know about this compound’s essential features, who can take it, and the impact of this medication on our body.

So what are we waiting for? Let’s find out every necessary detail about this medicinal compound to understand its efficiency better.

What drug is a Xanthine Oxidase Inhibitor?

What drug is a Xanthine Oxidase Inhibitor

What drug is a Xanthine Oxidase Inhibitor

The Xanthine Oxidase Inhibitor is a drug that restrains Xanthine Oxidase activity, an enzyme associated with purine metabolism. This drug reduces the production of Uric Acids in the human body, such as hyperuricemia and gout.

However, reducing urinary and serum uric acid concentration is not the only purpose this drug serves. It is also used in treating congestive heart failure and recurrent calcium oxalate calculi.

So if your doctors have suggested it, you don’t need to be worried as it is a safe and common medication and doesn’t come with any severe side-effects.

How Does Xanthine Oxidase Inhibitor Work?

If your body produces excessive uric acid and your kidneys couldn’t filter out enough of it, you will start facing some severe health issues. This overloaded uric acid will start forming sharp and tiny crystals in and around your joint.

Xanthine Oxidase medicine is used for treating kidney stones and gout. This drug works by reducing the amount of uric acid in your blood.

In gout, the joints of your body are swollen, and you can feel severe pain. And it happens when uric acid crystals start forming in your joints.

Additionally, when your kidneys are weak to sieve all the waste products in your body, including uric acid, stones start to form inside of this organ.

So this Xanthine Oxidase medication restrains the production of uric acids from giving you relief. Moreover, this drug is also prescribed to cancer patients. When treatments such as chemotherapy kill cancerous cells, uric acid is released from them.

Therefore, this inhibitor is used for removing the symptoms of excessive uric acid build-ups.

However, this inhibitor is not a quick remedy, and it may take several days to show its result. Hence, if you are about to take this medication, you need to have the patience to perform its job.

Is Allopurinol a Xanthine Oxidase Inhibitor?

Is Allopurinol a Xanthine Oxidase Inhibitor

Is Allopurinol a Xanthine Oxidase Inhibitor

Yes, Allopurinol is a Xanthine Oxidase Inhibitor drug and popularly used for treating conditions such as hyperuricemia and gout. It can be used for a long time without any problem per the doctor’s suggestion.

Now let me tell you how and when to take Allopurinol for better proficiency.

How to Take Allopurinol

The regular dose of Allopurinol is 100-300 mg. Your doctor will prescribe this medicine according to your health condition, and so you will know the perfect dosage for you.

Once you start taking this drug, your blood will be tested for uric acid levels, and if there is no change; your doctor may increase the dosage up to 900 mg.

However, if you have liver or kidney issues, you will be prescribed a lowered dosage and monitored by doctors.

Here’s the method you should use while ingesting this medicine:

  • Swallow the tablet with water
  • Make sure you are taking it after eating, not on an empty stomach.

Sometimes the doctors suggest you take this medicine with loads of fluid. If you’ve got that advice, you need to drink 2-3 liters of water per day. Moreover, it would be best if you tried to take the medicines every day for a better experience.

What will happen if I take too much Allopurinol?

If you accidentally take Allopurinol more than the prescribed dosage, you may feel discomfort such as,

  • Dizziness
  • Nausea and Vomiting
  • Stomach pain
  • Diarrhea
  • Headaches

So in this situation, it would be better if you go to the hospital immediately with someone’s help or call the ambulance to get proper treatment.

Is Allopurinol Bad for the Kidneys?

No, as Allopurinol reduces the amount of urate, it will not affect your kidneys even after long term use. But you need to take it according to your doctor’s suggestion, so make sure you’re not taking an excessive dosage.

But this medicine does have some severe side effects. So I am listing those so you can be cautious while taking this drug regularly.

Skin Rashes

One of the severe side effects of Allopurinol can be skin rashes. It may seem like an innocent effect, but it’s not! These rashes can be the beginning of Stevens-Johnson syndrome. And so, you need to be cautious if you get any symptoms like this.

First, you will get flu-like syndrome; then, you will get purple rashes to form blisters. Before the situation gets worsened, you need to consult your doctor for emergency treatment.

However, this side effect is pretty rare and develops in eight weeks after you start taking Allopurinol. So you don’t need to worry about this side effect at all.

Here are some other consequences that may happen if you take this medicine, looking at them for a better experience.

  • Yellow eyes or skin that may result in liver issues
  • High Fever, Sore throat, swollen gland
  • Get bruises without any reason.
  • Bleeding gums
  • Frequent urination
  • Unusual fatigue
  • Blurred Vision
  • Abnormal weight loss
  • I was feeling thirsty all the time.

Can I take painkillers with Allopurinol?

Yes, you can take painkillers and anti-inflammatory medicine such as Ibuprofen or Naproxen. But please ask for your doctor’s suggestion to avoid any hassle.

Moreover, inform your doctor if you are trying to get pregnant, already pregnant, or breastfeeding.

Final Verdict

The Xanthine Oxidase Inhibitor is a fantastic medicine to restrain Uric Acid production by your blood cells. It gives you relief from a dreadful disease such as gout and kidney issues.

So if you want the best result, always stick to the prescription and never go overboard at any cost.


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