Experts know there is a link between allergies and asthma. This is because children with allergie often also prone to asthma and a skin condition called atopic dermatitis ( eczema ).
Since allergy-triggering factors can lead to asthma attacks. Effective control of these allergies can lead to better asthma control. Knowing what the triggers are and avoiding them would help prevent asthma attacks.
Asthma symptoms may also trigger by exercise. A viral respiratory tract infection, and exposure to certain gases or fumes.
When trees and grasses start to grow in the spring, they produce a light. Also, powdery pollen that floats in the wind. If you are allergic to this pollen, you may experience the following symptoms: sniffling, sneezing, wheezing, runny nose, eye irritation, and tearing.
For some people with asthma, pollen can also trigger asthma. In this article we will tell you about Atlanta Allergy and asthma sandy springs. so let’s get started!
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Asthma is caused by a combination of complex genetic and environmental factors. It is a polygenic genetic disease, determined by the interaction of multiple genes.
Family genetic factors are risk factors in asthma. For example, after identical twins have asthma, the probability of the other having asthma is about 26%. The onset of allergic asthma has obvious family clustering.
It can be determined that the production of total IgE and specific IgE (sIgE). And also airway hyperresponsiveness control by specific genes.
Asthma has many genes. The GWAS analysis of over 20,000 patients found that the SNP sites of IL-18, TSLP, IL-33, SMAD3, HLA-DQ, ORMDL3, IL2RB, SLC22A5, IL-13. Also RORA genes related to asthma.
Many genes related to the inflammatory immune response. However, the sensitivity and contribution of specific genes to asthma needs further research.
Environmental factors are also the main cause of asthma. Both allergens and non-allergens can cause asthma. The main allergens include house dust mites, pollen, animal dander, cockroaches, and fungi.
Besides, some foods, including dairy products, aquatic products, wheat, grains, and meat, can also become allergens. The main non-allergens include ozone. Besides, chemical smog, car exhaust, infection, aspirin, chemical reagents, cold air, and exercise Wait.
However, the pathogenesis of asthma is very complicated. Both environmental factors and genetic factors play an important role. It is tough to estimate the proportion of the two in the affected population.
But I personally think that environmental factors have a great influence.
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There is a familial triad (asthma-eczema-rhinitis) that indicates allergic temperament. The environment, affected by technological progress, plays an equally important role in the growth of asthma. In some countries, it tripled.
Risk factors start at birth (!).
Low birth weight babies, lack breastfeeding, obesity, especially in girls, living in cities with modern amenities are risk factors.
There are a variety of allergens that can inhale inside and outside the home.
The most common is dust. That is full of various objects and microorganisms. Also, insect hairs and feces, mold, moisture, seeds and pollen of trees and flowers, detergents, and irritating chemicals.
Most air pollution does not cause asthma but worsens existing asthma.
The allergic reaction, in proportion to rhinitis transmitted.
Inflammation occupies the bronchi’s mucosal wall, narrows the lumen, and blocks it from thick mucus—the loop contracts and narrows.
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Asthma is a complex chronic inflammatory disease of the trachea. The occurrence of asthma involves the participation of a variety of immune cells and cytokines. The mechanism of its occurrence is also more complicated.
In recent years, studies found that natural immune cells include DC (dendritic cells), eosinophils, basophils and mast cells. Also adaptive immune cells, including CD4+ T cells, B cells, and NKT cells. Play an important role in asthma [1, 2].
At present, most research on asthma focused on allergic asthma, the most common type of asthma. In the past two decades, a large number of studies proved that the subtype Th2 of CD4+ T cells (helper type 2 T cells).
Besides, the cytokines IL-4 (interleukin 4), IL-5, and IL produced by it Type 2 immunity caused by -13 is the main cause of allergic asthma [3, 4].
In addition to Th2 cells and the cytokines produced by them involved in allergic asthma.
Recent studies found that Th9 (helper type 9 T cells) cells and the IL-9 produced by them (previously thought that IL-9 is produced by Th2 cells). It plays an important role in allergic diseases.
Such as allergic asthma and allergic dermatitis . Th2 and Th9 cells produce IL-4 (interleukin 4), and IL-9 can regulate antigen-specific IgE production (immunoglobulin E).
IL-4 also has the function of recruiting other inflammatory cells; IL-9 can Recruit and promote mast cells’ growth. IL-5 can promote eosinophils’ survival. IL-13 has pleiotropic properties, can cause tracheal hyperresponsiveness and tracheal tissue remodeling.
These are the main factors that promote lung airway inflammation and allergic asthma . The role of helper T cells and the cytokines they produce in asthma 
The development and differentiation of T cells with Wip1 gene deletion into Th9 cells. Their ability to secrete IL-9 are significantly lost.
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SENTA is an otolaryngology and allergy management service organization supported by Shore Capital Partners. It is committed to working with top physicians to establish a first-class network of otolaryngology and allergy treatment in the south.
Their mission is to be the partner and employer of choice for our doctors and team members. They look forward to taking this partnership to a new level to accelerate the already impressive history of Atlanta’s allergy in the local Atlanta community.
For nearly 50 years, Atlanta Allergy has been a leading provider of quality care, research, and clinical innovation in allergy, asthma, and immunology in the greater Atlanta metropolitan area and other Georgia areas.
Atlanta Allergy has 15 certified physicians and 10 Senior practicing physicians who provide services in 17 office locations. Besides, Atlanta Allergy is the only National Allergy Agency certified pollen counting station in the Atlanta area.
“For nearly 50 years, Atlanta Allergy and Asthma have been a leader in providing the most advanced allergy treatment in the Atlanta area. Atlanta Allergy and Asthma‘s goal is to provide special allergy services to more areas in Atlanta and beyond.
From the above discussion, I hope you know everything about asthma, and allergy, and this article will be useful to you.
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